Studies on peptides. L. Acidolysis of protecting groups in peptide chemistry by fluorosulphonic acid and methanesulphonic acid.

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Amino acid-protecting groups.

Albert Isidro-Llobet, Mercedes Álvarez, Fernando Albericio Institute for Research in Biomedicine, Barcelona Science Park, Baldiri Reixac 10, 08028Barcelona, Spain. CIBER-BBN, Networking Centre on Bioengineering, Biomaterials and Nanomedicine, Barcelona Science Park, Baldiri Reixac 10, 08028-Barcelona, Spain. Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona, 08028Bar...

متن کامل

Physical Chemistry Studies of Acid Dye Removal from Aqueous Media by Mesoporous Nano Composite: Adsorption Isotherm, Kinetic and Thermodynamic Studies

In this research, SBA-15/Polypyrrole (SBA-15/PPy) mesoporous nanocomposite was synthesized, characterized and applied for Acid Blue 62 (AB62) adsorption as a textile dye from aqueous solution. In order to evaluate the structural properties of synthesized adsorbent, FT-IR, FESEM and TEM images, XRD, and BET techniques were applied. Some parameters such as pH, dosage, and time which affect the ba...

متن کامل

Protecting Groups, Acid, Base, Temperature and Time

Factors affecting aspartimide formation, such as protecting groups, acidity, basicity, and temperature, were studied using the model tetrapeptide, Glu-AspGly-Thr. The aspartyl carboxyl side chain in this tetrapeptide was either free or protected as a benzyl or cyclohexyl ester. Our results showed that the cyclohexyl ester led to far less aspartimide formation during acidic or tertiary amine tre...

متن کامل

Understanding acid lability of cysteine protecting groups.

Cys-disulfide bonds contribute to the stabilization of peptide and protein structures. The synthesis of these molecules requires a proper protection of Cys residues, which is crucial to prevent side-reactions and also to achieve the correct Cys connectivity. Here we undertook a mechanistic study of a set of well-known acid-labile Cys protecting groups, as well other new promising groups, in ord...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Chemical and Pharmaceutical Bulletin

سال: 1975

ISSN: 0009-2363,1347-5223

DOI: 10.1248/cpb.23.1164